The goal of the Laboratory for Genomics Research (LGR) is to be a one-of-a-kind environment for collaboration between researchers at the University of California San Francisco (UCSF), the University of California Berkeley (UCB), and GlaxoSmithKline (GSK) committed to developing and deploying next-generation CRISPR technologies. The LGR represents a novel hybrid model that unites CRISPR pioneers with industry expertise under a single roof to work on projects both together and independently. Ultimately the aim is to deepen our understanding of genetics, discover new targets, and create next-generation technologies at scale that will become future standard practice for researchers across academia and industry.